In COVID-19 times, clinical trials are much more difficult to manage: Some trial centres are no longer available, on-site monitoring is reduced to the bare minimum, visits have to be cancelled or postponed, often even recruitment stops. The start of new studies that are not aimed at the prevention or control of COVID-19 is sometimes delayed indefinitely. How do you deal with this? With appropriate Urgent Safety Measures (USM) and good fine-tuning between sponsor, trial centres and all other parties involved. The rights and health of the trial subjects take priority over all other concerns. We at MEDIACC take care of this: With a certificate from TÜV Rheinland, our employees are well prepared for the changed situation and are able to solve problems flexibly.